To play the game I put the cards in a circle like so:
Then the student and I take turns picking a card, reading the question, and responding. Here is an example of the opposite side of the card:
Be sure to ask open ended follow up questions when the student answers.
At the end of the game, be sure to emphasis anything you may have in common. Students always have fun playing "20 questions", and I always learn valuable information about my student!
Could you play "20 questions" with your students?